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Pyruvate Kinase (PKM2) Antibody (C-term N491)

Pyruvate Kinase (PKM2) Antibody (C-term N491)

Item no.	ABC-AP7173A
Manufacturer	Abcepta
Amount	400 ul
Category	Metabolism Glucose Homeostasis Antibodies Western Blot
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Lehner, B., et al., Genome Res. 14(7):1315-1323 (2004). Gevaert, K., et al., Nat. Biotechnol. 21(5):566-569 (2003). Valentini, G., et al., J. Biol. Chem. 277(26):23807-23814 (2002). Lowrie, D.J. Jr., et al., J. Struct. Biol. 132(2):83-94 (2000). Williams, J.M., et al., Mol. Microbiol. 27(1):171-186 (1998).
NCBI	NP_001193725.1,NP_001193726.1,NP_001193727.1,NP_001193728.1,NP_002645.3,NP_872270.1,NP_872271.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Pyruvate kinase PKM,Cytosolic thyroid hormone-binding protein,CTHBP,Opa-interacting protein 3,OIP-3,Pyruvate kinase 2/3,Pyruvate kinase muscle isozyme,Thyroid hormone-binding protein 1,THBP1,Tumor M2-PK,p58,PKM,OIP3,PK2,PK3,PKM2
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Metabolism; Signal Transduction
Manufacturer - Targets	This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).
Bio Background	PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB05501
Gene Name	PKM
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Calculated Molecular Weight	57937
Antigen Source	HUMAN
Antigen Region	476-505
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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