MAPK10 Antibody (N-term)

Crown Antibodies; Primary Antibodies; Cancer; Immunology; Neuroscience; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies; RIG-l-like Receptor; Toll receptor signaling; Toll-Like receptor signaling; T cell activation; Interferon-gamma signaling; Apoptosis signaling; Mitochondrion

MAPK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kinase 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis.

RB03190

Purified Rabbit Polyclonal Antibody (Pab)

52585

7-34

WB: 1:1000
IHC-P: 1:25