Comparison

CCNA2 Antibody (C-term)

Item no. ABC-AP7292b
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products CCNA2, CCN1, CCNA, Cyclin-A2, Cyclin-A
Available
Primary Accession
P20248
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
Bio References
Henglein B., Proc. Natl. Acad. Sci. U.S.A. 91:5490-5494(1994)
Wang J., Nature 343:555-557(1990)
Tsang, W.Y., J. Cell Biol. 178 (4), 621-633 (2007)
Clonality
Polyclonal
Clone/Animal Names
RB14702
Gene ID
890
Gene Name
CCNA2 (HGNC:1578)
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of CCNA2 (arrow) using rabbit polyclonal CCNA2 Antibody (C-term) (Cat.#AP7292b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CCNA2 gene (Lane 2) (Origene Technologies).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with CCNA2 antibody (C-term) (Cat.#AP7292b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Isotype
Rabbit Ig
Calculated MW
48551
Antigen Region
358-389
Antigen Source
HUMAN
Target/Specificity
This CCNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human CCNA2.
NCBI Accession
NP_001228.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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