Comparison

TMPRSS2 Antibody (Center)

Item no. ABC-AP7377c
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, FC
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products TMPRSS2, PRSS10, Serine protease 10, Transmembrane protease serine 2 catalytic chain, Transmembrane protease serine 2, 3421-, Transmembrane protease serine 2 non-catalytic chain
Available
Primary Accession
O15393
Antigen Type
Synthetic Peptide
Application
WB, FC
Bio Background
TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.
Bio References
Gopalan, A., Cancer Res. 69 (4), 1400-1406 (2009)
Hofer, M.D., Cancer Res. 69 (2), 640-646 (2009)
Clonality
Polyclonal
Clone/Animal Names
RB18785
Gene ID
7113
Gene Name
TMPRSS2 (HGNC:11876)
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M
Legend image 1
Western blot analysis of TMPRSS2 antibody (Center) (Cat. #AP7377c) in HepG2 cell line lysates (35ug/lane). TMPRSS2 (arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
TMPRSS2 Antibody (Center) (Cat. #AP7377c) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 2
FC
Dilution image 2
1:10~50
Other Accession
Q9JIQ8
Predicted
M
Isotype
Rabbit Ig
Calculated MW
53859
Antigen Region
314-343
Antigen Source
HUMAN
Target/Specificity
This TMPRSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human TMPRSS2.
NCBI Accession
NP_001128571.1; NP_005647.3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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