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IDH1 Antibody (Center)

IDH1 Antibody (Center)

Item no.	ABC-AP7454c
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Sarcoma Myelofibrosis Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Astrocytoma By Organ Brain Cancer
Type	Antibody Polyclonal
Applications	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Geisbrecht B.V., Gould S.J.J. Biol. Chem. 274:30527-30533(1999) Xu X., Zhao J., Xu Z.J. Biol. Chem. 279:33946-33957(2004) Bleeker F.E., Lamba S.Hum. Mutat. 30:7-11(2009)
NCBI	NP_001269315.1,NP_001269316.1,NP_005887.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Isocitrate dehydrogenase [NADP] cytoplasmic,IDH,Cytosolic NADP-isocitrate dehydrogenase,IDP,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,IDH1,PICD
Similar products	IDH1, IDH, IDP, PICD, Cytosolic NADP-isocitrate dehydrogenase, Isocitrate dehydrogenase [NADP] cytoplasmic, Oxalosuccinate decarboxylase, NADP(+)-specific ICDH
Available
Manufacturer - Category	Primary Antibodies; Cancer; Metabolism; Signal Transduction; Catalog Updated
Manufacturer - Targets	This IDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-143 amino acids from the Central region of human IDH1.
Bio Background	IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB18238
Gene Name	IDH1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	B, Rat, Sh
Calculated Molecular Weight	46659
Antigen Source	HUMAN
Antigen Region	116-143
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:2000 IF: 1:10~50 WB: 1:1000 WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 2/5/2026

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