Comparison

AXL Antibody (C-term)

Item no. ABC-AP7602b
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products AXL, Tyrosine-protein kinase receptor UFO, UFO, AXL oncogene
Available
Primary Accession
P30530
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.
Bio References
Lee, S.T., et al., Oncogene 8(12):3403-3410 (1993).
Janssen, J.W., et al., Oncogene 6(11):2113-2120 (1991).
O'Bryan, J.P., et al., Mol. Cell. Biol. 11(10):5016-5031 (1991).
Partanen, J., et al., Proc. Natl. Acad. Sci. U.S.A. 87(22):8913-8917 (1990).
Clonality
Polyclonal
Clone/Animal Names
RB1483
Gene ID
558
Gene Name
AXL
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of anti-AXL C-term Pab (Cat. #AP7602b) in SKBR3 cell lysate. AXL (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2
IHC-P
Dilution image 2
1:50~100
Isotype
Rabbit Ig
Calculated MW
98337
Antigen Region
863-894
Antigen Source
HUMAN
Target/Specificity
This AXL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 863-894 amino acids from the C-terminal region of human AXL.
NCBI Accession
NP_001690.2; NP_068713.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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