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RET Antibody (C-term L1027)

RET Antibody (C-term L1027)

Item no.	ABC-AP7669d
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Adenocarcinoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Da Silva, A.M., et al., J. Clin. Endocrinol. Metab. 88(11):5438-5443 (2003). McWhinney, S.R., et al., J. Clin. Endocrinol. Metab. 88(10):4911-4916 (2003). D'Alessio, A., et al., Endocrinology 144(10):4298-4305 (2003). Soares, P., et al., Oncogene 22(29):4578-4580 (2003). Punales, M.K., et al., J. Clin. Endocrinol. Metab. 88(6):2644-2649 (2003).
NCBI	NP_065681.1,NP_066124.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Proto-oncogene tyrosine-protein kinase receptor Ret,Cadherin family member 12,Proto-oncogene c-Ret,Soluble RET kinase fragment,Extracellular cell-membrane anchored RET cadherin 120 kDa fragment,RET,CDHF12,CDHR16,PTC,RET51
Similar products	RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret, Soluble RET kinase fragment, Extracellular cell-membrane anchored RET cadherin 120 kDa fragment
Available
Manufacturer - Category	Primary Antibodies; Cancer; Signal Transduction; Anti-Kinome Antibodies
Manufacturer - Targets	This RET antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1012-1042 amino acids from the C-terminal region of human RET.
Bio Background	RET, a member of the cadherin superfamily, is one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This protein plays a crucial role in neural crest development, and the gene can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations i are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB01561
Gene Name	RET {ECO:0000303\|PubMed:2660074, ECO:0000312\|HGNC:HGNC:9967}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	124319
Antigen Source	HUMAN
Antigen Region	1012-1042
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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