« Back
Home /
BACE1 Antibody (N-term)

BACE1 Antibody (N-term)

Item no.	ABC-AP7774b
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BACE, BACE1, KIAA1149, Beta-secretase 1, Aspartyl protease 2, Beta-site amyloid precursor protein cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, ASP2, Asp 2, Beta-site APP cleaving enzyme 1
Available
Primary Accession	P56817
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Bio References	Xie, J., et al., J. Biol. Chem. 280(14):13824-13832 (2005). He, X., et al., J. Biol. Chem. 280(12):11696-11703 (2005). Huang, X.P., et al., J. Biol. Chem. 279(36):37886-37894 (2004). Chiocco, M.J., et al., J. Biol. Chem. 279(50):52535-52542 (2004). Yang, H.C., et al., J. Neurochem. 91(6):1249-1259 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB16874
Gene ID	23621
Gene Name	BACE1 (HGNC:933)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of anti-BACE1 Antibody (N-term) (Cat.#AP7774b) in mouse heart tissue lysates (35ug/lane). BACE1(arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Anti-BACE1 Antibody (N-term) at 1:1000 dilution + human pancreas lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 56 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human brain tissue reacted with BACE1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:10~50
Other Accession	P56819; P56818; Q2HJ40
Predicted	B, Rat
Isotype	Rabbit Ig
Calculated MW	55764
Antigen Region	38-70
Antigen Source	HUMAN
Target/Specificity	This BACE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-70 amino acids from the N-terminal region of human BACE1.
NCBI Accession	NP_001193978.1; NP_036236.1; NP_620427.1; NP_620428.1; NP_620429.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-AP7774b-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 400 ul

available

Delivery expected until 11/6/2025

Express Delivery: Save 14 days

Compare

Add to wishlist

Get an offer