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BACE1 Antibody (N-term)

BACE1 Antibody (N-term)

Item no.	ABC-AP7774b
Manufacturer	Abcepta
Amount	400 ul
Category	Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Xie, J., et al., J. Biol. Chem. 280(14):13824-13832 (2005). He, X., et al., J. Biol. Chem. 280(12):11696-11703 (2005). Huang, X.P., et al., J. Biol. Chem. 279(36):37886-37894 (2004). Chiocco, M.J., et al., J. Biol. Chem. 279(50):52535-52542 (2004). Yang, H.C., et al., J. Neurochem. 91(6):1249-1259 (2004).
NCBI	NP_001193978.1,NP_036236.1,NP_620427.1,NP_620428.1,NP_620429.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Beta-secretase 1,Aspartyl protease 2,ASP2,Asp 2,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,Memapsin-2,Membrane-associated aspartic protease 2,BACE1,BACE,KIAA1149
Similar products	BACE, BACE1, KIAA1149, Beta-secretase 1, Aspartyl protease 2, Beta-site amyloid precursor protein cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, ASP2, Asp 2, Beta-site APP cleaving enzyme 1
Available
Manufacturer - Category	Primary Antibodies; Cell Biology; Neuroscience
Manufacturer - Targets	This BACE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-70 amino acids from the N-terminal region of human BACE1.
Bio Background	Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is BACE. This protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB16874
Gene Name	BACE1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	B, Rat
Calculated Molecular Weight	55764
Antigen Source	HUMAN
Antigen Region	38-70
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 WB: 1:1000 IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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