PPP3CC Antibody (C-term)

Primary Antibodies; Antibody Collections; Signal Transduction; Amyotrophic Lateral Sclerosis (ALS); Anti-Wnt-Pathway (plus Lgr5) Antibodies; B cell receptor signaling; T cell activation; T cell receptor signaling

Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 6 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma, have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (9 to 95% amino acid identity).

RB6009

Purified Rabbit Polyclonal Antibody (Pab)

58129

482-512

WB: 1:1000
IHC-P: 1:50~100