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RB1 Antibody (C-term)

RB1 Antibody (C-term)

Item no.	ABC-AP8575B
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Flow Cytometry Immunohistochemistry Western Blot Senescence Primary Antibodies Astrocytoma By Organ Bladder Cancer Bone Cancer
Type	Antibody Polyclonal
Applications	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Connell-Crowley,L., et.al., Mol. Biol. Cell 8 (2), 287-301 (1997) Kitagawa,M., et.al., EMBO J. 15 (24), 7060-7069 (1996)
NCBI	NP_000312.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Retinoblastoma-associated protein,p105-Rb,pRb,Rb,pp110,RB1
Similar products	Rb, RB1, Retinoblastoma-associated protein, p105-Rb, pRb, pp110
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Viral process; Host-virus interaction
Manufacturer - Targets	This RB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 858-886 amino acids from the C-terminal region of human RB1.
Bio Background	RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. This protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB20715
Gene Name	RB1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	Rat
Calculated Molecular Weight	106159
Antigen Source	HUMAN
Antigen Region	858-886
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000 WB: 1:8000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/4/2025

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