C5 Antibody (N-term)

Primary Antibodies; Cell Biology; Immunology; Metabolism; Signal Transduction; Immunity; Inflammatory response; Innate immunity

C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.

RB21866

Affinity Purified Rabbit Polyclonal Antibody (Pab)

188305

253-281

WB: 1:1000
IHC-P: 1:50~100
FC: 1:10~50