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PKM2 (N-term E131) Antibody

PKM2 (N-term E131) Antibody

Item no.	ABC-AP9076a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PKM2, PKM, OIP3, PK2, PK3, Cytosolic thyroid hormone-binding protein, Opa-interacting protein 3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Thyroid hormone-binding protein 1, Tumor M2-PK, p58, CTHBP, THBP1, Pyruvate kinase PKM, OIP-3
Available
Primary Accession	P14618
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	PKM2 encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Bio References	Clower, C.V., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (5), 1894-1899 (2010) David, C.J., et.al., Nature 463 (7279), 364-368 (2010)
Clonality	Polyclonal
Clone/Animal Names	RB15338
Gene ID	5315
Gene Name	PKM
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of PKM2 (arrow) using rabbit polyclonal PKM2 Antibody (N-term E131) (Cat. #AP9076a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PKM2 gene (Lane 2) .
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	PKM2 (N-term E131) Antibody (Cat. #AP9076a) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PKM2 (N-term E131) Antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	PKM2 (N-term E131) Antibody (Cat. #AP9076a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	P11980; P11974; P52480
Predicted	M, Rb, Rat
Isotype	Rabbit Ig
Calculated MW	57937
Antigen Region	116-145
Antigen Source	HUMAN
Target/Specificity	This PKM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the N-terminal region of human PKM2.
NCBI Accession	NP_001193725.1; NP_001193726.1; NP_001193727.1; NP_001193728.1; NP_002645.3; NP_872270.1; NP_872271.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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