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SW116 (free base)

SW116 (free base)

Item no.	HY-120421
Manufacturer	MedChem Express
CASRN	1036759-00-8
Amount	1 ea
Category	Reagents & Chemicals Standards, Ladders & Markers
Type	Standard
Specific against	other
Citations	[1]Zeng C, et al. Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes[J]. Molecular imaging, 2011, 10(6): 7290.2011. 00009.
Smiles	O=[S](NCCCCCCCCCCN([C@]1([H])C2)[C@@](CCC1)([H])C[C@@H]2OC(NC(C=C3C)=C(C=C3)OC)=O)(C4=CC=CC5=C4C=CC=C5N(C)C)=O
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Sigma Receptor
Shipping Temperature	Room temperature
Molecular Weight	692.95
Product Description	SW116 free base is a selective fluorescent ligand for sigma-2 receptor with a Ki of 14 nM. SW116 free base exhibits in methanol a maximal excitation wavelength of 333 nM, and a maximal emission wavelength of 506 nM. SW116 free base can be internalized into MDA-MB-435 cells, and reach 50% maximum fluorescent intensity in 24 minutes. SW116 free base can be as a fluorescent probe used in cancer research[1].
Manufacturer - Research Area	Cancer
Manufacturer - Pathway	Neuronal Signaling
Isoform	Sigma 1 Receptor; Sigma 2 Receptor
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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