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TGF-βRI inhibitor 3

TGF-βRI inhibitor 3

Item no.	HY-137918
Manufacturer	MedChem Express
CASRN	666729-57-3
Amount	1 ea
Specific against	other
Citations	[1]Shimizu T, et al. Synthesis and evaluation of [2-(4-quinolyloxy)phenyl]methanone derivatives: novel selective inhibitors of transforming growth factor-beta kinase. J Med Chem. 2008 Jun 12;51(11):3326-9.
Smiles	CC(C1=CC(C)=C(C)C=C1OC2=CC=NC3=CC(OC)=C(OC)C=C23)=O
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Anaplastic lymphoma kinase (ALK); Src; TGF-β Receptor
Shipping Temperature	Room temperature
Molecular Weight	351.40
Product Description	TGF-βRI inhibitor 3 (Compound 9ac) is a selective TGF-β inhibitor. TGF-βRI inhibitor 3 can effectively inhibit the TGF-β signaling pathway. TGF-βRI inhibitor 3 has IC 50 values of 13 μM and 0.63 μM for c-Src kinase and ALK5 kinase, respectively [1] .
Manufacturer - Research Area	Others
Manufacturer - Pathway	Protein Tyrosine Kinase/RTK; TGF-beta/Smad
Clinical information	No Development Reported

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