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NCOA4-9a

NCOA4-9a

Item no.	HY-149457
Manufacturer	MedChem Express
CASRN	2650557-72-3
Amount	1 ea
Category	Reagents & Chemicals Standards, Ladders & Markers
Type	Standard
Specific against	other
Citations	[1]Yuying Fang, et al. Inhibiting Ferroptosis through Disrupting the NCOA4−FTH1 Interaction: A New Mechanism of Action. ACS Cent Sci. 2021 Jun 23;7(6):980-989.
Smiles	FC1=CC=C2C(CCN(C2)C3=CC=CC(C4=NC5=CC=C(N6CCN(CC6)C)C=C5N4)=C3)=C1
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Available
Product Description	NCOA4-9a inhibits ferroptosis by reducing the amount of bioavailable intracellular ferrous iron through disrupting the nuclear receptor coactivator 4 (NCOA4)−FTH1 (Ferritin) protein−protein interaction. NCOA4-9a inhibits Erastin (HY-15763)-induced ferroptosis, with EC50 of 0.29 μM in HT22 cells[1].
Shipping	Room temperature
MolecularWeight	441.54
Clinical Information	No Development Reported
Manufacturers Research Area	Others
Target	Ferroptosis
Manufacturers Target	Ferroptosis
Manufacturers Pathway	Apoptosis
Manufacturers Product type	Reference compound

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Amount: 1 ea

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