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Maleimide-PEG8-Val-Ala-PAB-SNS032

Maleimide-PEG8-Val-Ala-PAB-SNS032

Item no.	HY-161780
Manufacturer	MedChem Express
Amount	1 ea
Category	Reagents & Chemicals Amino Acid Derivates general
Type	Amino Acid Derivates
Specific against	other
Citations	[1]Cheung A, et al., Anti-EGFR antibody-drug conjugate carrying an inhibitor targeting CDK restricts triple-negative breast cancer growth. Clin Cancer Res. 2024 May 21.
Smiles	O=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC2=CC=C(COC(N3CCC(C(NC4=NC=C(SCC5=NC=C(C(C)(C)C)O5)S4)=O)CC3)=O)C=C2)=O)=O)=O)=O
Shipping Condition	Room temperature
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Category	Reference compound / Active compounds
Manufacturer - Targets	CDK; Drug-Linker Conjugates for ADC
Shipping Temperature	Room temperature
Molecular Weight	1274.50
Product Description	Maleimide-Val-Ala-PAB-SNS032 is a conjugate of ADC toxin and linker. SNS032 is an inhibitor for CDK, inhibiting the cell cycle at G1/S phase and cell viability of cancer cells. Maleimide-Val-Ala-PAB is a cleavable ADC linker. Maleimide-Val-Ala-PAB-SNS032 can be utilized for the synthesis of ADC molecules[1].
Manufacturer - Research Area	Cancer
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Clinical information	No Development Reported
UNSPSC Code	12352203

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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