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PRMT5 ligand 1

PRMT5 ligand 1

Item no.	HY-173092
Manufacturer	MedChem Express
CASRN	1616393-25-9
Amount	1 ea
Specific against	other
Citations	[1]Shen Y, et al., Discovery of First-in-Class Protein Arginine Methyltransferase 5 (PRMT5) Degraders. J Med Chem. 2020 Sep 10;63(17):9977-9989.
Smiles	O[C@@H](CNC(C1=NC=NC(NC2CNC2)=C1)=O)CN3CCC4=C(C=CC=C4)C3
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Histone Methyltransferase; Ligands for Target Protein for PROTAC
Shipping Temperature	Room temperature
Molecular Weight	382.46
Product Description	PRMT5 ligand 1 is the ligand for PRMT5 that can be used as target protein ligand for synthesis of PROTAC degrader MS4322 (HY-141877) [1] .
Manufacturer - Research Area	Cancer
Manufacturer - Pathway	Epigenetics; PROTAC
Clinical information	No Development Reported

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