Comparison

Bestatin HCl, 5 MG

Item no. AGSC-B-1075-5mg
Manufacturer AG Scientific
CASRN 65391-42-6
Amount 5 MG
Category
Type Inhibitors
Format Solid
Specific against other
Purity 0,98
InCHI 1S/ C16H24N2O4.ClH/ c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11;/ h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22);1H/ t12-,13+,14+;/ m1./ s1
Smiles CC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](Cc1ccccc1)N)O.Cl
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 65391-42-6
Available
Storage Conditions
-20°C
ChemACX
X1087674-3
Chemical Name
(2S)-2-[[(2S, 3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTANOYL]AMINO]-4-METHYLPENTANOIC ACID HYDROCHLORIDE
Description
Bestatin is a competitive, reversible protease inhibitor derived from Streptomyces olivoreticuli. Inhibits aminopeptidase enzymes, namely Aminopeptidase B, Aminopeptidase M (CD13), and leucine aminopeptidase (LAP3). Inhibition of these proteins by bestatin correlates to apoptosis induction in oncogenic cells. Bestatin is also a potent inhibitor of leukotriene A4 hydrolase (LTA4), potentially allowing investigation of the role of LTA4 in inflammation. It is being studied for use in the treatment ofacute myelocytic leukemia.
MDL Number
MFCD00058004
Melting Point
213-215°C
Solubility
Soluble in Methanol and Acetic Acid
Format
White Solid

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 MG
Available: In stock
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