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Bestatin

Bestatin

Item no.	AGSC-B-2547-25mg
Manufacturer	AG Scientific
CASRN	58970-76-6
Amount	25 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Heart & Blood Cancer Uterine, Ovarian & Cervical Cancer
Type	Inhibitors
Format	Solid
Specific against	other
Purity	>98% by HPLC
InCHI	1S/ C16H24N2O4/ c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/ h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/ t12-,13+,14+/ m1/ s1
Smiles	CC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](Cc1ccccc1)N)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	58970-76-6
Available
Storage Conditions	-20°C
Description	Bestatin is "pseudo"-dipeptide isolated from Streptomyces olivreticuli in 1976. Bestatin is a potent aminopeptidase B inhibitor with no carboxypeptidase activity. Bestatin acts as an immunomodulator by activating macrophages and T lymphocytes. Bestatin also exhibits antitumor activity and has been investigated in clinical trials. Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer 1 p> . 1.) Tsukamoto H, Shibata K, Kajiyama H, Terauchi M, Nawa A, Kikkawa F. 2008. Aminopeptidase N (APN)/CD13 inhibitor, Ubenimex, enhances radiation sensitivity in human cervical cancer. BMC Cancer. 8:74.
MDL Number	MFCD00083262
Melting Point	233-236 °C
Solubility	Soluble in water (<1 25), DMSO (2 mg/ml), methanol (5 mg/ml), 1eq NaOH (50 mM), ethanol (<1 mg/ml at 25 °C), acetic acid, aq HCl, and alkaline solution Insoluble in ethyl acetate, benzene, hexane, and chloroform
Boiling Point	604.66 °C at 760 mmHg
Format	White solid

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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Delivery expected until 9/25/2025

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