Comparison

Cycloheximide, 50 G

Item no. AGSC-C-1189-50g
Manufacturer AG Scientific
CASRN 66-81-9
Amount 50 G
Category
Type Inhibitors
Format Solid
Specific against other
Purity 0,95
InCHI 1S/ C15H23NO4/ c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/ h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/ t8-,9-,11-,12+/ m0/ s1
Smiles C[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)C
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 66-81-9
Available
Storage Conditions
+4°C
ChemACX
X1006248-5
Chemical Name
4-[(2R)-2-[(1S, 3S, 5S)-3, 5-DIMETHYL-2-OXOCYCLOHEXYL]-2-HYDROXYETHYL]PIPERIDINE-2, 6-DIONE
Description
A very active antibiotic against many yeasts and fungi. Inhibits protein synthesis in eukaryotes (but not in prokaryotes) by interfering with the translocation step. It inhibits chain initiation as well as chain elongation by acting on the 60S subunit of the eukaryote ribosome, interacting directly with enzyme translocase. Cycloheximide is used as an inhibitor to study cell-free protein biosynthesis in eukaryotes and also used to block ribosome-dependent in vivo polypeptide synthesis. It induces apoptosis in a variety of cells, but can also delay or inhibit apoptosis by other agents. Cycloheximide’ slongstanding application as a gene selection antibiotic, has a powerful new role in Genome editing utilizing the CRISPR/Cas9 system 1 . A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families. Cycloheximide is in stock call for bulk quotations, typical lead for subdivision, packing and shipping larger quantities is 7-14 days. Research size order 100mg 250mg lead is shorter. International Shipping of this material can be subject to an additional hazardous shipping fee.
MDL Number
MFCD00082346
Solubility
Soluble in Chloroform, Ethanol and Methanol.
Boiling Point
491.8±; 10.0 °C at 760 mmHg
Format
White Solid

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 G
Available: In stock
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