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Oligomycin A, 5 MG

Oligomycin A, 5 MG

Item no.	AGSC-O-1063-5mg
Manufacturer	AG Scientific
CASRN	579-13-5
Amount	5 MG
Category	Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Format	Solid
Specific against	other
Purity	0,95
InCHI	1S/ C45H74O11/ c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/ h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-1
Smiles	CC[C@H]1CC[C@@H]2[C@@H]([C@@H]([C@H]([C@@]3(O2)CC[C@H]([C@H](O3)C[C@H](C)O)C)C)OC(=O)/C=C/[C@H]([C@@H]([C@H](C(=O)[C@H]([C@@H]([C@H](C(=O)[C@@]([C@@H]([C@H](C/C=C/C=C1)C)O)(C)O)C)O)C)C)O)C)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	579-13-5
Available
Storage Conditions	+4°C
ChemACX	X1094055-9
Chemical Name	(1R, 2'R, 4E, 5'S, 6S, 6'S, 7R, 8S, 10R, 11R, 12S, 14R, 15S, 16R, 18E, 20E, 22R, 25S, 28S, 29R)-22-ETHYL-7, 11, 14, 15-TETRAHYDROXY-6'-((R)-2-HYDROXYPROPYL)-5', 6, 8, 10, 12, 14, 16, 28, 29-NONAMETHYL-3', 4', 5', 6'-TETRAHYDRO-2, 26-DIOXASPIRO[BICYCLO[23.3.1]NONACOSA[4, 18, 20]TRIENE-27, 2'-
Description	Oligomycin A is a component of the oligomycin complex (O-1060). It is an inhibitor of ATP synthase. In oxidative phosphorylation research, it is used to prevent state 3 (phosphorylating) respiration. Oligomycin A inhibitsATP synthase by blocking its proton channel (Fo subunit), which is necessary foroxidative phosphorylationofADPtoATP(energy production). The inhibition of ATP synthesis by oligomycin A will significantly reduce electron flow through theelectron transport chain however, electron flow is not stopped completely due to a process known as proton leak or mitochondrial coupling. This process is due to thefacilitated diffusionof protons into themitochondrial matrixthrough anuncoupling proteinsuch asthermogenin, orUCP1. Stimulates lysosome acidification due to shunting of membrane potential. Induces apoptosis in a variety of cell types. Oligomycin A also induces autophagy in the IPLB-LdFB insect cell line. Bulk available, inquire for pricing details.
MDL Number	MFCD00065705
Melting Point	140-141°C
Solubility	Soluble in DMSO
Boiling Point	886.3±; 65.0 °C at 760 mmHg
Format	White to Light Brown Solid

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 MG

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Delivery expected until 9/25/2025

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