« Back
Home /
RMC-6291

RMC-6291

Item no.	DCC-DC60452-5mg
Manufacturer	DCChemicals
CASRN	2641998-63-0
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Smiles	C(N1C2=CC=C3N4CCOC(CC(C(N5CCCC(N5)C(OCC(CC(C2=C3)=C1C1C=CC=NC=1C(C)OC)(C)C)=O)=O)NC(=O)C(C(C)C)N(C)C(C1(CCN(CC1)C(=O)C#CC(C)(C)N(C)C)F)=O)C4)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Manufacturer - Applications	RMC-6291 is a potent covalent inhibitor of KRASG12C(ON) that forms a tri-complex within tumor cells between KRASG12C(ON) and cyclophilin A (CypA). RMC-6291 overcomes limitations of first-generation KRASG12C(OFF) inhibitors in preclinical models by directly targeting the active form of this important oncogenic driver.
Molecular Weight	1012.26173734665

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5 mg

available

Delivery expected until 3/5/2026

Express Delivery: Save 6 days

Compare

Add to wishlist

Get an offer