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KWCN-41

KWCN-41

Item no.	DCC-DC65344-100mg
Manufacturer	DCChemicals
CASRN	2913223-17-1
Amount	100 mg
Category	Blocking Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Applications	Blocking
Specific against	other
Smiles	O=C(N1CCOCC1)C2=CC=C(C3=CC4=C(N3)N=CC=C4)C=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Manufacturer - Applications	KWCN-41 is a selective and efficient inhibitor of RIPK1 kinase with an IC50 value of 88 nM. KWCN-41, specifically inhibiting cell necroptosis but not apoptosis, protects cell survival by blocking the necroptotic pathway, which inhibits the phosphorylation of essential proteins of the necroptosis. It also prevented the development of inflammation and reduced the level of inflammatory factors in mice. KWCN-41 is expected to be a lead compound for further studies in inflammatory diseases.
Molecular Weight	307, 353

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 9/25/2025

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