Ro24-7429

Item no.	HY-19149-25mg
Manufacturer	MedChem Express
CASRN	139339-45-0
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.89
Citations	[1]A H Patki, et al. HIV-1 Tat protein and its inhibitor Ro 24-7429 inhibit lymphocyte proliferation and induce apoptosis in peripheral blood mononuclear cells from healthy donors. Cell Immunol. 1996 Apr 10;169(1):40-6.\|[2]Michael O'Hare, et al. Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators. Am J Pathol. 2021 Jul;191(7):1193-1208.
Smiles	CNC1=NC2=CC=C(Cl)C=C2C(C3=CC=CN3)=NC1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-anti-virus
Manufacturer - Targets	Apoptosis; HIV
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	272.73
Product Description	Ro24-7429 is a potent and orally active HIV-1 transactivator protein Tat antagonist. Ro24-7429 is also a runt-related transcription factor 1 (RUNX1) inhibitor. Ro24-7429 has anti-HIV, antifibrotic and anti-inflammatory effects[1][2].
Manufacturer - Research Area	Cancer; Infection; Inflammation/Immunology
Solubility	DMSO: 62.5 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Apoptosis
Isoform	HIV-1
Clinical information	No Development Reported

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HY-19149-25mg-safety-datasheet.pdf