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Aszonapyrone A

Aszonapyrone A

Item no.	TMO-T35754-5mg
Manufacturer	TargetMol
CASRN	83103-08-6
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	0,98
Smiles	[H][C@@]12CC[C@@]3(C)[C@H](Cc4c(O)cc(C)oc4=O)C(=C)CC[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)C2(C)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	456.623
Description	Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.1, 2, 3 It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively).1 Aszonapyrone A is active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation.2 It is also active against P. falciparum in vitro (IC50 = 1.34 μg/ml).3
Pathways	Others

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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