Comparison

Biotin-labeled ODN 2216 (sodium) European Partner

Item no. HY-150741A-1ea
Manufacturer MedChem Express
Amount 1 ea
Category
Type Separation, Purification
Specific against other
Citations [1]He Y, et al. Hepatic mitochondrial DNA/Toll-like receptor 9/MicroRNA-223 forms a negative feedback loop to limit neutrophil overactivation and acetaminophen hepatotoxicity in mice. Hepatology. 2017 Jul;66(1):220-234.
[2]Huang L, et al. CpG-based immunotherapy impairs antitumor activity of BRAF inhibitors in a B-cell-dependent manner. Oncogene. 2017 Jul 13;36(28):4081-4086.
[3]Krug A, et al. Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells. Eur J Immunol. 2001 Jul;31(7):2154-63.
[4]Li Y, et al. A novel antagonist of TLR9 blocking all classes of immunostimulatory CpG-ODNs. Vaccine. 2011 Mar 3;29(11):2193-8.
[5]Okada T, et al. Murine thymic plasmacytoid dendritic cells. Eur J Immunol. 2003 Apr;33(4):1012-9.
Smiles [Biotin-labeled ODN 2216 (sodium)]
ECLASS 10.1 32170301
ECLASS 11.0 32170301
UNSPSC 41104900
Shipping Condition Room temperature
Available
Manufacturer - Type
Oligonucleotides
Manufacturer - Applications
COVID-19-immunoregulation
Manufacturer - Targets
Toll-like Receptor (TLR)
Shipping Temperature
Room temperature
Product Description
Biotin-labeled ODN 2216 (sodium) is a human-specific TLR9 (toll-like receptor 9) ligand or agonist. Biotin-labeled ODN 2216 (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
Manufacturer - Research Area
Inflammation/Immunology
Solubility
10 mM in H2O
Manufacturer - Pathway
Immunology/Inflammation
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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