Comparison

SARS Protein Detection Set

Item no. PRS-PSI-1810-1Set
Manufacturer ProSci
Amount 1 Set
Category
Type Detection Sets
Format Liquid
Applications WB, IF, IHC
Specific against Human (Homo sapiens)
Citations Marra MA, Jones SJ, Astell CR, et al. The Genome sequence of the SARS-associated corona virus. Science 2003; 300:1399-404.
Rota PA, Oberste MS, Monroe SS, et al. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 2003; 300:1394-9.
Navas-Nartin SR and Weiss S. Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development. J. Neurovirol. 2004; 10:75-85.
Li W, Moore MJ, Vasileva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 2003; 426:450-4.
ECLASS 10.1 32161090
ECLASS 11.0 32161090
UNSPSC 41116126
Available
Storage Conditions
Stable at 4°C for three months, store at -20°C for up to one year.
Background
A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral S (Spike) protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. The M protein (Membrane protein, Matrix protein) is another major structural viral protein. It is an integral membrane protein involved in the budding of the viral particles and interacts with S protein and the nucleocapsid protein. The SARS E protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. ACE2, the SARS receptor, normally plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis.

For images please see PDF data sheet
Set Contents
ACE2 Antibody (IN1), Catalog No. 3215 (50 μg)

SARS Envelope Antibody (CT), Catalog No. 3533 (50 μg)

SARS Matrix Antibody (CT), Catalog No. 3529 (50 μg)

SARS Spike Antibody (CT), Catalog No. 3525 (50 μg)

SARS Envelope Peptide (CT), Catalog No. 3533P

SARS Matrix Peptide (CT), Catalog No. 3529P

SARS Spike Peptide (CT), Catalog No. 3525P
Purification
Antibodies are supplied as affinity chromatography purified IgG.
Concentration
Antibody 1 mg/mL

Peptide 200 μg/mL
Buffer
PBS containing 0.02% sodium azide.
Immunogen
Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.
Clonality
Polyclonal
Disclaimer
This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 Set
Available: In stock
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