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PDX1 Mouse Monoclonal Antibody [Clone ID: LBI2A12]

PDX1 Mouse Monoclonal Antibody [Clone ID: LBI2A12]

Item no.	LBI-AMM08930VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Metabolism Diabetes Glucose Homeostasis Antibodies
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI2A12
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	PDX1
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Maturity onset diabetes of the young, Type II diabetes mellitus
Overview	Carrier-free (BSA/glycerol-free) Pdx1 mouse monoclonal antibody, clone LBI2A12
Immunogen	Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Gene Name	Homo sapiens pancreatic and duodenal homeobox 1 (PDX1), mRNA.
Symbol	PDX1
Function	Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
Summary	Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:20000, IHC 1:50, IF 1:50~100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Maturity onset diabetes of the young, Type II diabetes mellitus

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

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