FGF1 Mouse Monoclonal Antibody [Clone ID: LBI4D2]

FGF1

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Human recombinant protein fragment corresponding to amino acids 16-155 of human AFGF (NP_000791) produced in E.coli.

FGF1

FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described.

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)