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BubR1 (BUB1B) Mouse Monoclonal Antibody [Clone ID: LBI11G2]

BubR1 (BUB1B) Mouse Monoclonal Antibody [Clone ID: LBI11G2]

Item no.	LBI-AMM09208V
Manufacturer	Leading Biology
Amount	100 ul
Category	Oncology Antibodies By Organ Lung Cancer Skin Cancer Colorectal Cancer Breast Cancer
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI11G2
Specific against	Human (Homo sapiens), Monkey (Cynomolgus, Simian)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Bub1A, BUB1beta, BUBR1, hBUBR1, MAD3L, MVA1, SSK1
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	BUB1B
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Cell cycle
Overview	Anti-BUB1B (BubR1) mouse monoclonal antibody, clone LBI11G2
Immunogen	Full-length protein expressed in 293T cell transfected with human BUB1B expression vector
Gene Name	BUB1 mitotic checkpoint serine/threonine kinase B
Symbol	BUB1B
Function	Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Summary	This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome(APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000 IHC 1:50 IF 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Cell cycle

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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