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ERAB (HSD17B10) Mouse Monoclonal Antibody [Clone ID: LBI11A2]

ERAB (HSD17B10) Mouse Monoclonal Antibody [Clone ID: LBI11A2]

Item no.	LBI-AMM09371V
Manufacturer	Leading Biology
Amount	100 ul
Category	Neuroscience Metabolism Diabetes Neural Mitochondrial Function Antibodies
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI11A2
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	HSD17B10
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation
Overview	HSD17B10 mouse monoclonal antibody, clone LBI11A2
Immunogen	Full length human recombinant protein of human HSD17B10 (NP_004484) produced in HEK293T cell.
Gene Name	hydroxysteroid 17-beta dehydrogenase 10
Symbol	HSD17B10
Function	Druggable Genome
Summary	This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.89 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, IHC 1:50, IF 1:50~100, FLOW 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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