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Hexokinase II (HK2) Mouse Monoclonal Antibody [Clone ID: LBI4C5]

Hexokinase II (HK2) Mouse Monoclonal Antibody [Clone ID: LBI4C5]

Item no.	LBI-AMM09492VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Metabolism Glucose Homeostasis Antibodies
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI4C5
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	HKII, HXK2
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	HK2
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus
Overview	Carrier-free (BSA/glycerol-free) HK2 mouse monoclonal antibody, clone LBI4C5
Immunogen	Full length human recombinant protein of human HK2 (NP_000180) produced in HEK293T cell.
Gene Name	Homo sapiens hexokinase 2 (HK2), transcript variant 1, mRNA.
Symbol	HK2
Function	Druggable Genome
Summary	Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways.This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:1000, IF 1:100, Flow 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

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