Comparison

CD5 Mouse Monoclonal Antibody [Clone ID: LBI6F7]

Item no. LBI-AMM09936V
Manufacturer Leading Biology
Amount 100 ul
Category
Type Antibody Monoclonal
Format Liquid
Clone LBI6F7
Specific against Human (Homo sapiens), Monkey (Cynomolgus, Simian)
Host Mouse
Isotype IgG1
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias LEU1, T1
Available
Manufacturer - Category
mAbs-V
Manufacturer - Targets
CD5
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Hematopoietic cell lineage
Overview
Anti-CD5 mouse monoclonal antibody, clone LBI6F7
Immunogen
Full length human recombinant protein of human CD5 (NP_055022) produced in HEK293T cell.
Gene Name
CD5 molecule
Symbol
CD5
Function
Druggable Genome, Transmembrane
Summary
CD5 (Lymphocyte antigen T1/Leu-1) is a transmembrane glycoprotein which has been implicated as a receptor in the regulation of T-cell proliferation (1). CD5 is part of the scavenger receptor cysteine-rich (SRCR) family group B and it is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by T cell leukemia, lymphomas, and activated T cells. Occasionally, CD5 antigen is also expressed on a subset of B cells. Mantle cell lymphomas (same as diffuse centrocytic lymphomas) are CD5+ while the follicle center cell lymphomas are CD5. A ligand for CD72/LYB-2, CD5 has been linked to negative regulation of T cell and B cell receptors signaling (2).
Manufacturer - Format
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
0.96 mg/ml
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution
WB 1:500~2000, FLOW 1:100
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Hematopoietic cell lineage

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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