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FADD Mouse Monoclonal Antibody [Clone ID: LBI1C11]

FADD Mouse Monoclonal Antibody [Clone ID: LBI1C11]

Item no.	LBI-AMM10027V
Manufacturer	Leading Biology
Amount	100 ul
Category	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cell Status Apoptosis
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI1C11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GIG3, MORT1
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	FADD
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Alzheimer's disease, Apoptosis, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Overview	Anti-FADD mouse monoclonal antibody, clone LBI1C11
Immunogen	Full length human recombinant protein of human FADD (NP_003815) produced in HEK293T cell.
Gene Name	Fas associated via death domain
Symbol	FADD
Function	Druggable Genome
Summary	The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, FLOW 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Alzheimer's disease, Apoptosis, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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