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Desmin (DES) Mouse Monoclonal Antibody [Clone ID: LBI4G1]

Desmin (DES) Mouse Monoclonal Antibody [Clone ID: LBI4G1]

Item no.	LBI-AMM10809VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Antibodies Cell Biology Cytoskeleton Intermediate filaments
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI4G1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CDCD3, CMD1F, CSM1, CSM2, LGMD1D, LGMD1E, LGMD2R
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	DES
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
Overview	Carrier-free (BSA/glycerol-free) DES mouse monoclonal antibody, clone LBI4G1
Immunogen	Human fragment corresponding to amino acids 104-391 of human DES (NP_001918) produced in E.coli.
Gene Name	Homo sapiens desmin (DES), transcript variant 1, mRNA.
Symbol	DES
Function	Druggable Genome
Summary	This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:200~500, IHC 1:150, FLOW 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

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