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MVK Mouse Monoclonal Antibody [Clone ID: LBI 1D7]

MVK Mouse Monoclonal Antibody [Clone ID: LBI 1D7]

Item no.	LBI-AMM11304V
Manufacturer	Leading Biology
Amount	100 ul
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Enzymes Other Fatty Acid Enzymes
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI 1D7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	LRBP, MK, MVLK, POROK3
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	MVK
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Metabolic pathways, Terpenoid backbone biosynthesis
Overview	MVK mouse monoclonal antibody, clone LBI 1D7
Immunogen	Full length human recombinant protein of human MVK (NP_000422) produced in HEK293T cell.
Gene Name	mevalonate kinase
Symbol	MVK
Function	Druggable Genome
Summary	This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, IF 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Metabolic pathways, Terpenoid backbone biosynthesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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