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Cytochrome P450 17A1 (CYP17A1) Mouse Monoclonal Antibody [Clone ID: LBI3F11]

Cytochrome P450 17A1 (CYP17A1) Mouse Monoclonal Antibody [Clone ID: LBI3F11]

Item no.	LBI-AMM11690V
Manufacturer	Leading Biology
Amount	100 ul
Category	Oncology Antibodies By Cell Type
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI3F11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CPT7, CYP17, P450C17, S17AH
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	CYP17A1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	C21-Steroid hormone metabolism, Metabolic pathways
Overview	CYP17A1 mouse monoclonal antibody, clone LBI3F11
Immunogen	Full length human recombinant protein of human CYP17A1(NP_000093) peoduced in HEK293T cell.
Gene Name	cytochrome P450 family 17 subfamily A member 1
Symbol	CYP17A1
Function	Druggable Genome, P450
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, IHC 1:150, FLOW 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	C21-Steroid hormone metabolism, Metabolic pathways

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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