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PMS2 Mouse Monoclonal Antibody [Clone ID: LBI2G5]

PMS2 Mouse Monoclonal Antibody [Clone ID: LBI2G5]

Item no.	LBI-AMM13919VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Glioma Hematology Lymphoma Melanoma Sarcoma Mesothelioma
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI2G5
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	HNPCC4, PMS2CL, PMSL2
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	PMS2
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Mismatch repair
Overview	Carrier-free (BSA/glycerol-free) PMS2 mouse monoclonal antibody, clone LBI2G5
Immunogen	Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell.
Gene Name	Homo sapiens PMS1 homolog 2, mismatch repair system component (PMS2), transcript variant 1, mRNA.
Symbol	PMS2
Function	Druggable Genome
Summary	This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:500, IHC 1:150, IF: 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Mismatch repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

Express Delivery: Save 17 days

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