Comparison

PMS2 Mouse Monoclonal Antibody [Clone ID: LBI4B7]

Item no. LBI-AMM13921V
Manufacturer Leading Biology
Amount 100 ul
Category
Type Antibody Monoclonal
Format Liquid
Clone LBI4B7
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias HNPCC4, MLH4, PMS2CL, PMSL2
Available
Manufacturer - Category
mAbs-V
Manufacturer - Targets
PMS2
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Mismatch repair
Overview
PMS2 mouse monoclonal antibody, clone LBI4B7
Immunogen
Full length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell.
Gene Name
PMS1 homolog 2, mismatch repair system component
Symbol
PMS2
Function
Druggable Genome
Summary
This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008]
Manufacturer - Format
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
1 mg/ml
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution
WB 1:500, IHC 1:150, IF: 1:100
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Mismatch repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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