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SPHK1 Mouse Monoclonal Antibody [Clone ID: LBI1A6]

SPHK1 Mouse Monoclonal Antibody [Clone ID: LBI1A6]

Item no.	LBI-AMM14195VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Enzymes Fatty Acid Catabolism
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI1A6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	SPHK
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	SPHK1
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Calcium signaling pathway, Fc gamma R-mediated phagocytosis, Metabolic pathways, Sphingolipid metabolism, VEGF signaling pathway
Overview	Carrier-free (BSA/glycerol-free) SPHK1 mouse monoclonal antibody, clone LBI1A6
Immunogen	Full length human recombinant protein of human SPHK1(NP_068807) produced in HEK293T cell.
Gene Name	Homo sapiens sphingosine kinase 1 (SPHK1), transcript variant 1, mRNA.
Symbol	SPHK1
Function	Druggable Genome
Summary	The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:400~4000, IHC 1:150, IF 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Calcium signaling pathway, Fc gamma R-mediated phagocytosis, Metabolic pathways, Sphingolipid metabolism, VEGF signaling pathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

Express Delivery: Save 21 days

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