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PCNA Mouse Monoclonal Antibody [Clone ID: LBI4B2]

PCNA Mouse Monoclonal Antibody [Clone ID: LBI4B2]

Item no.	LBI-AMM14864V
Manufacturer	Leading Biology
Amount	100 ul
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation By Organ Bladder Cancer
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI4B2
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ATLD2
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	PCNA
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair
Overview	Mouse monoclonal anti-PCNA antibody, clone 4B2, Loading, clone LBI4B2
Immunogen	Full length human recombinant protein of human PCNA (NP_002583) produced in E.coli.
Gene Name	proliferating cell nuclear antigen
Symbol	PCNA
Function	Druggable Genome, Stem cell - Pluripotency
Summary	The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, IHC 1:150
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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