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P Glycoprotein (ABCB1) Mouse Monoclonal Antibody [Clone ID: LBI1A3]

P Glycoprotein (ABCB1) Mouse Monoclonal Antibody [Clone ID: LBI1A3]

Item no.	LBI-AMM14929V
Manufacturer	Leading Biology
Amount	100 ul
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Sarcoma
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI1A3
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ABC20, CD243, CLCS, GP170, MDR1, p-170, P-GP, PGY1
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	ABCB1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	ABC transporters
Overview	ABCB1 mouse monoclonal antibody, clone LBI1A3
Immunogen	Human recombinant protein fragment corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) produced in SF9 cell.
Gene Name	ATP binding cassette subfamily B member 1
Symbol	ABCB1
Function	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Summary	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:1000
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	ABC transporters

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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