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p95 NBS1 (NBN) Mouse Monoclonal Antibody [Clone ID: LBI2E9]

p95 NBS1 (NBN) Mouse Monoclonal Antibody [Clone ID: LBI2E9]

Item no.	LBI-AMM14985VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI2E9
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	AT-V1, AT-V2, ATV, NBS, NBS1, P95
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	NBN
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Homologous recombination
Overview	Carrier-free (BSA/glycerol-free) NBN mouse monoclonal antibody, clone LBI2E9
Immunogen	Human recombinant protein fragment corresponding to amino acids 461-754 of human NBN (NP_002476) produced in E.coli.
Gene Name	Homo sapiens nibrin (NBN), transcript variant 1, mRNA.
Symbol	NBN
Function	Druggable Genome
Summary	Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:2000, IHC 1:150
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Homologous recombination

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

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