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DOT1L Mouse Monoclonal Antibody [Clone ID: LBI1D8]

DOT1L Mouse Monoclonal Antibody [Clone ID: LBI1D8]

Item no.	LBI-AMM15511VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI1D8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	DOT1, KMT4
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	DOT1L
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Lysine degradation
Overview	Carrier-free (BSA/glycerol-free) DOT1L mouse monoclonal antibody, clone LBI1D8
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-434 of human DOT1L (NP_115871) produced in E.coli.
Gene Name	Homo sapiens DOT1 like histone lysine methyltransferase (DOT1L), mRNA.
Symbol	DOT1L
Function	Druggable Genome
Summary	The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:2000, IHC 1:150
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Lysine degradation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

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