Comparison

BMP4 Mouse Monoclonal Antibody [Clone ID: LBI1D1]

Item no. LBI-AMM16083VCF
Manufacturer Leading Biology
Amount 100 ug
Category
Type Antibody Monoclonal
Format Lyophilized
Clone LBI1D1
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2b
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
Available
Manufacturer - Category
mAbs-V
Manufacturer - Targets
BMP4
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, TGF-beta signaling pathway
Overview
Carrier-free (BSA/glycerol-free) BMP4 mouse monoclonal antibody, clone LBI1D1
Immunogen
Human recombinant protein fragment corresponding to amino acids 293-408 of human BMP4 (NP_001193) produced in E.coli.
Gene Name
Homo sapiens bone morphogenetic protein 4 (BMP4), transcript variant 1, mRNA.
Symbol
BMP4
Function
Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway
Summary
This gene encodes a member of the bone morphogenetic protein (BMP) family of proteins, which is part of the transforming growth factor-beta (TGF-beta) superfamily. Members of the BMP family play an important role in bone and cartilage development. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Manufacturer - Format
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution
WB 1:500
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, TGF-beta signaling pathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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