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Acid sphingomyelinase (SMPD1) Mouse Monoclonal Antibody [Clone ID: LBI10C5]

Acid sphingomyelinase (SMPD1) Mouse Monoclonal Antibody [Clone ID: LBI10C5]

Item no.	LBI-AMM16472VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Enzymes Fatty Acid Catabolism
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI10C5
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ASM, ASMASE, NPD
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	SMPD1
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Lysosome, Metabolic pathways, Sphingolipid metabolism
Overview	Carrier-free (BSA/glycerol-free) SMPD1 mouse monoclonal antibody, clone LBI10C5
Immunogen	Human recombinant protein fragment corresponding to amino acids 62-341 of human SMPD1 (NP_000534) produced in E.coli.
Gene Name	Homo sapiens sphingomyelin phosphodiesterase 1 (SMPD1), transcript variant 1, mRNA.
Symbol	SMPD1
Function	Druggable Genome, Transmembrane
Summary	The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:200
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Lysosome, Metabolic pathways, Sphingolipid metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

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