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PARP1 Mouse Monoclonal Antibody [Clone ID: LBI5F1]

PARP1 Mouse Monoclonal Antibody [Clone ID: LBI5F1]

Item no.	LBI-AMM16725VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Melanoma Sarcoma
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI5F1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ADPRT, ADPRT 1, ADPRT1, ARTD1, pADPRT-1, PARP, PARP-1, PPOL
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	PARP1
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Base excision repair
Overview	Carrier-free (BSA/glycerol-free) PARP1 mouse monoclonal antibody, clone LBI5F1
Immunogen	Full length human recombinant protein of human PARP1 (NP_001609) produced in E.coli.
Gene Name	Homo sapiens poly(ADP-ribose) polymerase 1 (PARP1), mRNA.
Symbol	PARP1
Function	Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Summary	This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:2000, IHC 1:150
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Base excision repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

Express Delivery: Save 17 days

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