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RET Mouse Monoclonal Antibody [Clone ID: LBI21H4]

RET Mouse Monoclonal Antibody [Clone ID: LBI21H4]

Item no.	LBI-AMM17079V
Manufacturer	Leading Biology
Amount	100 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Adenocarcinoma
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI21H4
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	RET
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Endocytosis, Pathways in cancer, Thyroid cancer
Overview	RET mouse monoclonal antibody, clone LBI21H4
Immunogen	Human recombinant protein fragment corresponding to amino acids 713-1017 of human RET(NP_066124) produced in E.coli.
Gene Name	ret proto-oncogene
Symbol	RET
Function	Druggable Genome, Protein Kinase, Transmembrane
Summary	This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, IHC 1:150
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Endocytosis, Pathways in cancer, Thyroid cancer

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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