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PDX1 Mouse Monoclonal Antibody [Clone ID: LBI7F7]

PDX1 Mouse Monoclonal Antibody [Clone ID: LBI7F7]

Item no.	LBI-AMM17831V
Manufacturer	Leading Biology
Amount	100 ul
Category	Metabolism Diabetes Glucose Homeostasis Antibodies
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI7F7
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	PDX1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Maturity onset diabetes of the young, Type II diabetes mellitus
Overview	PDX1 mouse monoclonal antibody, clone LBI7F7
Immunogen	Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Gene Name	pancreatic and duodenal homeobox 1
Symbol	PDX1
Function	Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
Summary	The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Maturity onset diabetes of the young, Type II diabetes mellitus

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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