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IL12RB1 Mouse Monoclonal Antibody [Clone ID: LBI1A6]

IL12RB1 Mouse Monoclonal Antibody [Clone ID: LBI1A6]

Item no.	LBI-AMM18192V
Manufacturer	Leading Biology
Amount	100 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Senescence Astrocytoma By Organ Bladder Cancer Bone Cancer
Type	Antibody Monoclonal
Format	Liquid
Clone	LBI1A6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD212, IL-12R-BETA1, IL12RB, IMD30
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	IL12RB1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Overview	IL12RB1 mouse monoclonal antibody, clone LBI1A6
Immunogen	Human recombinant protein fragment corresponding to amino acids 33-283 of human IL12RB1(NP_714912) produced in E.coli.
Gene Name	interleukin 12 receptor subunit beta 1
Symbol	IL12RB1
Function	Druggable Genome, Transmembrane
Summary	The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:500
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/15/2026

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